Diabetes Research Centre

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Trial Net Type 1 Diabetes Natural History Study

Updated May 9, 2007

Type 1 diabetes is a life-long condition that can affect both children and adults. It occurs when the body attacks and destroys the cells in the pancreas that make insulin. The body needs insulin, a hormone, to turn food into energy. The goal of this study is to increase our understanding of how type 1 diabetes develops over time. Better understanding may help to prevent diabetes or develop a cure.

Relatives of people with type 1 diabetes have a 10 to 15 times greater risk for the disease than people without a family history. Diagnosis of type 1 diabetes is not usually made until the person presents with symptoms, but the disease can start months to years before this.

This study will identify people at increased risk and observe them over time. The study is divided into 3 phases with separate consent required for each. Phase 1 will identify people at risk using autoantibody testing. Those identified will enter Phase 2 which is a single visit to assess the level of risk. This is followed by Phase 3, which involves 6 monthly risk assessments for 5 years. Eligible participants would be offered participation in prevention trials as these become available.

Click here to read more about the TrialNet Natural History Study, or follow one of the links below to learn about specific aspects of the trial.

Participation criteria for the TrialNet Natural History Study

Contact people for the TrialNet Natural History Study

Download Information Brochure for TrialNet Natural History Study

Find your local TrialNet Site - updated May 9, 2007!

The Natural History Study is supported by Type 1 Diabetes TrialNet (click on icon below to learn more about TrialNet)

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Diabetes Research Centre

Last updated 19 December, 2007. For further information about this website, please contact Catherine McLean