Diabetes Research Centre

Towards the prevention and cure of diabetes

WEHI

Diabetes Research Centre

Melbourne, Australia

Diabetes Research at the Walter + Eliza Hall Institute of Medical Research and the Royal Melbourne Hospital

RMH

 

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Publications

Updated 4 June, 2009

*** Page under construction - please come back soon! ***

 

2009

Chan AC, Serwecinska L, Cochrane A, Harrison LC, Godfrey DI, Berzins SP (2009). Immune characterization of an individual with an exceptionally high natural killer T cell frequency and her immediate family. Clin Exp Immunol 156:238-245. [View Abstract]

Couper JJ, Beresford S, Hirte C, Baghurst PA, Pollard A, Tait BD, Harrison LC, Colman PG (2009). Weight gain in early life predicts risk of islet autoimmunity in children with a first-degree relative with type 1 diabetes. Diabetes Care. 32:94-99. [View Abstract]

Graco M, Berlowitz DJ, Fourlanos S, Sundram S (2009). Depression is greater in non-English speaking hospital outpatients with type 2 diabetes. Diabetes Res Clin Pract 83:e51-e53. [View Abstract]

Honeyman MC, Harrison LC (2009). Congenital rubella, diabetes and HLA. Diabetologia 52:371-372. [View Abstract]

Mannering SI, Pang SH, Williamson NA, Naselli G, Reynolds EC, O'Brien-Simpson NM, Purcell AW, Harrison LC (2009). The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes. Clin Exp Immunol 156:226-231. [View Abstract]

O'Connell MA, Donath S, O'Neal DN, Colman PG, Ambler GR, Jones TW, Davis EA, Cameron FJ (2009). Glycaemic impact of patient-led use of sensor-guided pump therapy in type 1 diabetes: a randomised controlled trial. Diabetologia 52:1250-1257. [View Abstract]

Rajamani K, Colman PG, Li LP, Best JD, Voysey M, D'Emden MC, Laakso M, Baker JR, Keech AC; FIELD study investigators (2009). Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespecified analysis of a randomised controlled trial. Lancet. 373:1780-1788. [View Abstract]

2008

Fourlanos S, Harrison LC, Colman PG (2008). The accelerator hypothesis and increasing incidence of type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 15:321-325. [View Abstract]

Fourlanos S, Varney MD, Tait BD, Morahan G, Honeyman MC, Colman PG, Harrison LC (2008). The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes. Diabetes Care. 31:1546-1549. [View Abstract]

Harrison LC, Honeyman MC, Morahan G, Wentworth JM, Elkassaby S, Colman PG, Fourlanos S (2008). Type 1 diabetes: lessons for other autoimmune diseases? J Autoimmun. 31:306-310. [View Abstract]

Harrison LC (2008). Vaccination against self to prevent autoimmune disease: the type 1 diabetes model. Immunol Cell Biol. 86:139-145. [View Abstract]

Wentworth JM, Gao N, Sumithran KP, Maartens NF, Kaye AH, Colman PG, Ebeling PR (2008). Prospective evaluation of a protocol for reduced glucocorticoid replacement in transsphenoidal pituitary adenomectomy: prophylactic glucocorticoid replacement is seldom necessary. Clin Endocrinol (Oxf) 68:29-35. [View Abstract]

2007

Barker JM, McFann K, Harrison LC, Fourlanos S, Krischer J, Cuthbertson D, Chase HP, Eisenbarth GS; DPT-1 Study Group (2007). Pre-type 1 diabetes dysmetabolism: maximal sensitivity achieved with both oral and intravenous glucose tolerance testing. J Pediatr. 150:31-36. [View Abstract]

Goodall I, Colman PG, Schneider HG, McLean M, Barker G (2007). Desirable performance standards for HbA(1c) analysis - precision, accuracy and standardisation: consensus statement of the Australasian Association of Clinical Biochemists (AACB), the Australian Diabetes Society (ADS), the Royal College of Pathologists of Australasia (RCPA), Endocrine Society of Australia (ESA), and the Australian Diabetes Educators Association (ADEA). Clin Chem Lab Med 45:1083-1097. [View Abstract]

Honeyman MC, Elkassaby S, Harrison LC (2007). Honeyman MC, Elkassaby S, Harrison LC. Diabetes Care 30:e118. [View Abstract]

Keech AC, Mitchell P, Summanen PA, O'Day J, Davis TM, Moffitt MS, Taskinen MR, Simes RJ, Tse D, Williamson E, Merrifield A, Laatikainen LT, d'Emden MC, Crimet DC, O'Connell RL, Colman PG; FIELD study investigators (2007). Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial. Lancet 370:1687-1697. [View Abstract]

Schneider HG, Goodall I, Colman PG, McLean M, Barker G; Australian Working Party for HbA1c standardization (2007). New haemoglobin A1c: the way it is reported is about to change... Intern Med J 37:213-215. [View Abstract]

Wentworth JM, Harrison LC (2007). Does insulin resistance need resistin? J Clin Endocrinol Metab 92:2036-2037. [View Abstract]

2006

Fourlanos S, Perry C, Stein MS, Stankovich J, Harrison LC, Colman PG (2006). A clinical screening tool identifies autoimmune diabetes in adults. Diabetes Care. 29:970-975. [View Abstract]

Locke NR, Stankovic S, Funda DP, Harrison LC (2006). TCR gamma delta intraepithelial lymphocytes are required for self-tolerance. J Immunol 176:6553-6559. [View Abstract]

Narendran P, Neale AM, Lee BH, Ngui K, Steptoe RJ, Morahan G, Madsen O, Dromey JA, Jensen KP, Harrison LC (2006). Proinsulin is encoded by an RNA splice variant in human blood myeloid cells. Proc Natl Acad Sci USA 103:16430-16435. [View Abstract]

Wraight PR, Lawrence SM, Campbell DA, Colman PG (2006). Retrospective data for diabetic foot complications: only the tip of the iceberg? Intern Med J 36:197-199. [View Abstract]

2005

Fourlanos S, Harrison LC (2005). Insulin resistance in children and adolescents with type 1 diabetes mellitus: relation to obesity. Pediatr Diabetes 6:3-4. [View Abstract]

Fourlanos S, Dotta F, Greenbaum CJ, Palmer JP, Rolandsson O, Colman PG, Harrison LC (2005). Latent autoimmune diabetes in adults (LADA) should be less latent. Diabetologia 48:2206-2212. [View Abstract]

Harrison LC (2005). The prospect of vaccination to prevent type 1 diabetes. Hum Vaccin 1:143-50. [View Abstract]

Lee P, Nicoll AJ, McDonough M, Colman PG (2005). Substance abuse in young patients with type 1 diabetes: easily neglected in complex medical management. Intern Med J 35:359-361. [View Abstract]

Mannering SI, Harrison LC, Williamson NA, Morris JS, Thearle DJ, Jensen KP, Kay TW, Rossjohn J, Falk BA, Nepom GT, Purcell AW (2005). The insulin A-chain epitope recognized by human T cells is posttranslationally modified.  J Exp Med 202:1191-1197. [View Abstract]

Narendran P, Estella E, Fourlanos S (2005). Immunology of type 1 diabetes. QJM 98:547-556. [View Abstract]

Wraight PR, Lawrence SM, Campbell DA, Colman PG (2005). Creation of a multidisciplinary, evidence based, clinical guideline for the assessment, investigation and management of acute diabetes related foot complications. Diabet Med. 22:127-136. [View Abstract]

2004

Fourlanos S, Narendran P, Byrnes GB Colman PG Harrison LC (2004). Insulin resistance is a risk factor for progression to type 1 diabetes. Diabetologia 47:1661-1667. [View Abstract]

Harrison LC, Honeyman MC, Steele C, Stone NL, Sarugeri E, Bonifacio E, Couper JJ, Colman PG (2004). Pancreatic beta-cell function and immune responses to insulin following administration of intranasal insulin to humans at-risk for type 1 diabetes. Diabetes Care 27:2348-2355. [View Abstract]

Harrison LC, Fourlanos S, Every A, Honeyman MC, Steptoe RJ, Martinez NR, Jensen KP, Funda DP, Mannering SI, Colman PG, Narendran P (2004). Prevention of type 1 diabetes. In: International Textbook of Diabetes Mellitus (Ferranini E, Zimmet P, De fronzo R and Keen H, Eds). John Wiley & Sons, Chichester, UK. 3rd Ed, 115, pp1879-1898. [View Abstract]

Hussein Z, Wentworth JM, Nankervis AJ, Proietto J, Colman PG (2004). Effectiveness and side effects of thiazolidinediones for type 2 diabetes: real-life experience from a tertiary hospital. Med J Aust 181:536-539. [View Abstract]

Lawrence SM, Wraight PR, Campbell DA, Colman PG (2004). Assessment and management of inpatients with acute diabetes-related foot complications: room for improvement. Intern Med J 34:229-233. [View Abstract]

Mannering SI, Morris JS, Stone NL, Jensen KP, VAN Endert PM, Harrison LC (2004). CD4+ T cell proliferation in response to GAD and proinsulin in healthy, pre-diabetic, and diabetic donors. Ann N Y Acad Sci 1037:16-21. [View Abstract]

2003

Fourlanos S Colman PG, Harrison LC (2003). Late-onset autoimmune diabetes in relatives of people with type 1 diabetes. Ann NY Acad Sci 1005:370-373. [View Abstract]

Greenbaum CJ, Harrison LC (2003). Guidelines for intervention trials in subjects with newly-diagnosed type 1 diabetes. Diabetes 52:1059-1065. [View Abstract]

von Herrath MG, Harrison LC (2003) Antigen-induced regulatory T cells in autoimmunity. Nature Reviews Immunology 3:223-232. [View Abstract]

2002

Colman PG, McNair PD, Gellert S, Kewming K, Schmidli RS, Steele CE, Harrison LC (2002). Development of autoantibodies to islet antigens is not restricted to early childhood: implications for pre-clinical type 1 diabetes screening. Pediatric Diabetes 3:144-148. [View Abstract]

Petrovsky N, Kyvik KO, Bonnevie-Nielsen V, Beck-Nielsen H, Green A, Harrison LC (2002). Evidence from twin studies for acquired cellular immune hyperreactivity in type 1 diabetes. Immunology 106:584-589. [View Abstract]

2001

Hänninen A, Braakhuis A, Heath WR, Harrison LC (2001). Mucosal antigen primes diabetogenic cytotoxic T lymphocytes regardless of dose or delivery route. Diabetes 50:771-775. [View Abstract]

Harrison LC (2001) Risk assessment, prediction and prevention of type 1 diabetes. Pediatric Diabetes 2: 71-82. [View Abstract]

Solly NR, Honeyman MC, Harrison LC (2001) The mucosal interface between 'self' and 'non-self' determines the impact of environment on autoimmune diabetes. Curr Dir Autoimmun 4:68-90. [View Abstract]

2000

Colman PG, Steele C, Couper JJ, Beresford SJ, Powell T, Kewming K, Pollard A, Gellert S, Tait B, Honeyman M, Harrison LC (2000) Islet autoimmunity in infants with a type 1 diabetes relative is common but usually restricted to one autoantibody. Diabetologia 43:203-209. [View Abstract]

Colman PG, McNair P, King J, Caudwell J, Jankulovski C, PG, Tait BD, Honeyman MC, Harrison LC (2000) Screening for preclinical type 1 diabetes in a discrete population with an apparent increased disease incidence. Pediatric Diabetes 1:193-198. [View Abstract]

Couper J, Pollard A, Kallincos N, Colman PG, Honeyman MC, Harrison LC, Rischmueller M (2000) Toxic shock syndrome associated with newly-diagnosed type 1 diabetes. J Pediatr Child Health 36:279-282. [View Abstract]

Hänninen A, Harrison LC (2000) Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model. Immunological Rev 173:109-119. [View Abstract]

Harrison LC, Hafler D. Novel therapeutic strategies in autoimmune diseases: antigen-specific (2000) Curr Opin Immunol 12:704-711. [View Abstract]

Honeyman MC, Coulson BS, Stone NL, Gellert SA, Goldwater PN, Steele CE, Couper JJ, Tait BD, Colman PG, Harrison LC (2000) Association between rotavirus infection and pancreatic islet autoimmunity in children at-risk for type 1 diabetes. Diabetes 49:1319-1324. [View Abstract]

Honeyman MC, Coulson BS, Harrison LC (2000) Rotavirus is a candidate cause of pancreatitis leading to type 1 diabetes. N Engl J Med 342:1835-1837. [View Abstract]

1999

Couper JJ, Steele C, Beresford S, Powell T, McCaul K, Pollard A, Gellert S, Jankulovski C, Harrison LC, Colman PG (1999) Lack of association between duration of breast feeding and introduction of cows' milk and development of islet autoimmunity. Diabetes 48:2145-2149. [View Abstract]

Harrison LC, Honeyman MC (1999) Cows' milk and type 1 diabetes. The real issue is mucosal immune function. Diabetes 48:1501-1507. [View Abstract]

1998

Couper JJ, Harrison LC, Aldis JE, Colman PG, Honeyman MC, Ferrante A (1998) IgG subclass antibodies to glutamic acid decarboxylase and risk for progression to clinical insulin-dependent diabetes. Human Immunol 59:493-499. [View Abstract]

1997

Honeyman MC, Brusic V, Harrison LC (1997) Strategies for identifying and predicting islet autoantigen T-cell epitopes in insulin-dependent diabetes. Ann Med 29:402-404. [View Abstract]

Honeyman MC, Stone N, DeAizpurua HJ, Rowley MJ, Harrison LC (1997) High T-cell responses to the glutamic acid decarboxylase (GAD) isoform 67 reflect a hyperimmune state that precedes the onset of insulin-dependent diabetes. J Autoimmunity 10:165-173. [View Abstract]

Noorchashm H, Kwok W, Rabinovitch A, Harrison LC (1997) Immunology of type 1 diabetes. Diabetologia 40:B50-B57. [View Abstract]

1996

Harrison LC, Dempsey-Collier M, Kramer DR, Takahashi K (1996) Aerosol insulin induces CD8 gamma-delta T cells that suppress murine insulin-dependent diabetes. J Exp Med 184:2167-2174. [View Abstract]

1995

Tait BD, Harrison LC, Drummond B, Stewart V, Varney M, Honeyman MC (1995) HLA antigens and age at onset of insulin-dependent diabetes. Human Immunol 42:116-122. [View Abstract]

 

 

 

 

Diabetes Research Centre

Last updated 23 February, 2010. For further information about this website, please contact Rhiannon Jones